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. Author manuscript; available in PMC: 2016 Feb 20.
Published in final edited form as: J Chromatogr A. 2015 Jan 10;1382:48–64. doi: 10.1016/j.chroma.2014.12.086

Table 5.

Microdialysis-Microchip Electrophoresis Devices

Interface Region Analytes On- or Off-line Material(s) Detection Comments Reference
Flow-gated in vitro Enzamatic reaction
monitoring
fluorescein and FMG
On-line Glass LIF First report of MD-ME [38]
Flow-gated Brain
(striatum)
Effect of PDC on
glutamate
On-line Glass LIF (OPA derivatized) [137]
Pneumatic
valves
in vitro Fluorescein,
dichlorofluorescein
On-line PDMS/glass LIF First report of MD-ME with
pneumatic valving interface
[90]
Flow-gated in vitro Amino acids On-line Glass LIF (NDA/2-ME derivatized) [89]
Pneumatic
valves
in vitro Dopamine from PC12
cells
On-line PDMS/glass EC (carbon ink electrodes
with Pd decoupler)
First report of MD-ME-EC [111]
Segmented
flow
Brain
(striatum)
Effect of PDC on
amino acids
On-line Glass LIF (NDA/CN derivatized) First report of segmented
flow MD-ME
[143]
Flow-gated Brain
(striatum)
Fluorescein and
amino acids
Pseudo-on-line PDMS LIF (NDA/CN derivatized [91]
Pneumatic
valves
in vitro Catecholamines On-line PDMS/glass EC (carbon ink microarray
with Pd decoupler)
[127]
Segmented
flow
Brain
(striatum)
Effect of PDC or high
K+ on amino acids
Off-line Glass LIF (NDA/CN derivatized) Droplets formed at MD
headpiece
[144]
Segmented
flow
Brain
(striatum)
Effect of K+
microinjections on
amino acids
Off-line Glass LIF (NDA/CN derivatized) [145]
Pneumatic
valves
in vitro Catecholamines On-line PDMS/epoxy EC (Pt electrode and Pd
decoupled imbedded in
epoxy)
[126]
Flow-gated in vitro Amino acids and an
internal standard
On-line PDMS LIF (NDA/CN derivatized) [92]
Flow-gated in vitro Enzymatic reaction
monitoring hydrogen
peroxide
On-line Glass EC (Pt electrodes) [110]
Flow-gated in vitro Catecholamines On-line PDMS/glass EC (PPF electode) [146]
Flow-gated Subcutaneous Nitrite On-line Glass EC (Pt electrodes) On-animal (sheep) [84]