Table 5.
Interface | Region | Analytes | On- or Off-line | Material(s) | Detection | Comments | Reference |
---|---|---|---|---|---|---|---|
Flow-gated | in vitro | Enzamatic reaction monitoring fluorescein and FMG |
On-line | Glass | LIF | First report of MD-ME | [38] |
Flow-gated | Brain (striatum) |
Effect of PDC on glutamate |
On-line | Glass | LIF (OPA derivatized) | [137] | |
Pneumatic valves |
in vitro | Fluorescein, dichlorofluorescein |
On-line | PDMS/glass | LIF | First report of MD-ME with pneumatic valving interface |
[90] |
Flow-gated | in vitro | Amino acids | On-line | Glass | LIF (NDA/2-ME derivatized) | [89] | |
Pneumatic valves |
in vitro | Dopamine from PC12 cells |
On-line | PDMS/glass | EC (carbon ink electrodes with Pd decoupler) |
First report of MD-ME-EC | [111] |
Segmented flow |
Brain (striatum) |
Effect of PDC on amino acids |
On-line | Glass | LIF (NDA/CN derivatized) | First report of segmented flow MD-ME |
[143] |
Flow-gated | Brain (striatum) |
Fluorescein and amino acids |
Pseudo-on-line | PDMS | LIF (NDA/CN derivatized | [91] | |
Pneumatic valves |
in vitro | Catecholamines | On-line | PDMS/glass | EC (carbon ink microarray with Pd decoupler) |
[127] | |
Segmented flow |
Brain (striatum) |
Effect of PDC or high K+ on amino acids |
Off-line | Glass | LIF (NDA/CN derivatized) | Droplets formed at MD headpiece |
[144] |
Segmented flow |
Brain (striatum) |
Effect of K+ microinjections on amino acids |
Off-line | Glass | LIF (NDA/CN derivatized) | [145] | |
Pneumatic valves |
in vitro | Catecholamines | On-line | PDMS/epoxy | EC (Pt electrode and Pd decoupled imbedded in epoxy) |
[126] | |
Flow-gated | in vitro | Amino acids and an internal standard |
On-line | PDMS | LIF (NDA/CN derivatized) | [92] | |
Flow-gated | in vitro | Enzymatic reaction monitoring hydrogen peroxide |
On-line | Glass | EC (Pt electrodes) | [110] | |
Flow-gated | in vitro | Catecholamines | On-line | PDMS/glass | EC (PPF electode) | [146] | |
Flow-gated | Subcutaneous | Nitrite | On-line | Glass | EC (Pt electrodes) | On-animal (sheep) | [84] |