Fig 4. Experimental vs. MVA derived KOR scores.

KOR scores were computed for several gene-essentiality datasets from DEG, which were experimentally determined on synthetic lab media. Each horizontal error bar marks the computationally derived KOR score bounds found by ECOEDS and the small red rectangle marks the experimental DEG KOR score. Where available, both SEED and curated models were used. The DEG KOR scores for all organisms (but one—B. thailandensis, not shown) scored within the predicted computational bounds.