Table 2. Characteristics of included studies focused on protein expression of LEP.
| First author | Year | Ethnicity | Sample | Sample size | Gender (M/F) | Age (years) | Method | NOS score | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | ||||||
| Karvonen-Gutierrez CA[18] | 2013 | Mixed | Blood | 98 | 444 | - | - | 46.0 ± 2.6 | 46.1 ± 2.8 | ELISA | 7 |
| Beekhuizen M[28] | 2012 | Mixed | SF | 18 | 16 | 172/262 | 340/292 | 71.7 ± 0.1 | 69.8 ± 0.1 | ELISA | 6 |
| de Boer TN[29] | 2012 | Caucasians | Blood | 172 | 132 | 53/119 | 34/98 | 67.4 ± 8.4 | 56.5 ± 4.5 | ELISA | 8 |
| Ku JH[16] | 2009 | Asians | SF | 42 | 10 | 15/27 | 7/3 | 62.1 ± 10.5 | 36.4 ± 11.4 | ELISA | 6 |
| Wang ZH[20] | 2007 | Asians | Blood | 67 | 30 | 24/43 | 11/19 | 64.0 ± 17.2 | 63.0 ± 13.3 | RIA | 6 |
Legends: M—male, F—female, ELISA—enzyme linked immunosorbent assay, RIA—radioimmunoassay, NOS—Newcastle-Ottawa Scale