Table 2.
Cognitive Domain | Neuropsychological Test | No. | Mean | GM PAD, rho | p | WM PAD, rho | p |
---|---|---|---|---|---|---|---|
Processing speed | Trail Making Test A, s | 90 | 29.59 (12.15) | 0.338 | 0.001a | 0.379 | <0.001a |
Trail Making Test B, s | 90 | 68.79 (39.79) | 0.343 | 0.001a | 0.271 | 0.009a | |
Stroop color naming, s | 90 | 34.47 (8.83) | 0.279 | 0.007a | 0.281 | 0.006a | |
Stroop word reading, s | 90 | 23.93 (5.49) | 0.269 | 0.009a | 0.306 | 0.003a | |
Choice reaction task median reaction time, ms | 66 | 478 (124) | 0.331 | 0.005a | 0.243 | 0.047 | |
Executive function | Trail Making Test B minus A, s | 90 | 39.15 (32.51) | 0.262 | 0.011a | 0.154 | 0.146 |
Inhibition/switching, s | 89 | 69.54 (22.18) | 0.247 | 0.018a | 0.205 | 0.053 | |
Inhibition/switching minus baseline Stroop performance, s | 89 | 37.24 (18.41) | 0.213 | 0.043 | 0.168 | 0.115 | |
Letter fluency total | 89 | 39.01 (12.73) | −0.271 | 0.009a | −0.133 | 0.214 | |
Intellectual ability | WASI similarities | 90 | 37.04 (5.22) | −0.160 | 0.132 | −0.136 | 0.200 |
WASI matrix reasoning | 88 | 26.34 (5.53) | −0.104 | 0.336 | 0.013 | 0.908 | |
Memory | People Test immediate recall | 90 | 22.94 (7.33) | −0.253 | 0.015a | −0.254 | 0.014a |
Correlations with PAD score were conducted with variance accounting for chronological age partialed out, using the Spearman rank-order approach.
Denotes statistical significance after false discovery rate correction for multiple comparisons.
GM* gray matter; PAD * predicted age difference score; TBI * traumatic brain injury; WASI * Wechsler Abbreviated Scale for Intelligence; WM * white matter.