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. 2015 Mar 25;77(4):571–581. doi: 10.1002/ana.24367

Table 2.

Relationship between Neuropsychological Measures and PAD in TBI Patients

Cognitive Domain Neuropsychological Test No. Mean GM PAD, rho p WM PAD, rho p
Processing speed Trail Making Test A, s 90 29.59 (12.15) 0.338 0.001a 0.379 <0.001a
Trail Making Test B, s 90 68.79 (39.79) 0.343 0.001a 0.271 0.009a
Stroop color naming, s 90 34.47 (8.83) 0.279 0.007a 0.281 0.006a
Stroop word reading, s 90 23.93 (5.49) 0.269 0.009a 0.306 0.003a
Choice reaction task median reaction time, ms 66 478 (124) 0.331 0.005a 0.243 0.047
Executive function Trail Making Test B minus A, s 90 39.15 (32.51) 0.262 0.011a 0.154 0.146
Inhibition/switching, s 89 69.54 (22.18) 0.247 0.018a 0.205 0.053
Inhibition/switching minus baseline Stroop performance, s 89 37.24 (18.41) 0.213 0.043 0.168 0.115
Letter fluency total 89 39.01 (12.73) −0.271 0.009a −0.133 0.214
Intellectual ability WASI similarities 90 37.04 (5.22) −0.160 0.132 −0.136 0.200
WASI matrix reasoning 88 26.34 (5.53) −0.104 0.336 0.013 0.908
Memory People Test immediate recall 90 22.94 (7.33) −0.253 0.015a −0.254 0.014a

Correlations with PAD score were conducted with variance accounting for chronological age partialed out, using the Spearman rank-order approach.

a

Denotes statistical significance after false discovery rate correction for multiple comparisons.

GM* gray matter; PAD * predicted age difference score; TBI * traumatic brain injury; WASI * Wechsler Abbreviated Scale for Intelligence; WM * white matter.