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. 2014 Oct 31;35(4):1442–1450. doi: 10.1111/liv.12699

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© 2014 The Authors. Liver International Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Serum alkaline phosphatase levels in NOD.c3c4 receiving no antiretroviral therapy. (A) Serial measurement of serum alkaline phosphatase in the NOD.c3c4 mice showing variance in individual levels as well as a reduction mean levels as mice aged, mainly from 8 to 12 weeks (P < 0.0001, 1 way anova). (B) Reduction in serum alkaline phosphatase levels from baseline levels between 8 and 12 weeks, showing diminished reduction in NOD.c3c4 vs. NOD.GFP (Data shown as means ± SEM, ***P < 0.001, t-test).