Table 2. Identified variables by Cox Multivariate Regression Analysis in the training cohort.
| Variable | B | p | Exp(B) | 95.0% CI for Exp(B) |
|---|---|---|---|---|
| Tumor length (cm) | ||||
| <3.0 | 1 | |||
| 3.0–4.9 | 0.109 | 0.592 | 1.116 | 0.746–1.669 |
| 5.0–7.9 | 0.365 | 0.074 | 1.441 | 0.963–2.157 |
| ≥8 | 0.590 | 0.026 | 1.805 | 1.072–3.040 |
| Number of positive lymph nodes (N stage) | ||||
| 0 (N0) | 1 | |||
| 1–2 (N1) | 0.426 | 0.019 | 1.532 | 1.072–2.189 |
| 3–6 (N2) | 0.821 | 0.001 | 2.274 | 1.384–3.736 |
| ≥7 (N3) | 1.299 | 0.000 | 3.666 | 1.923–6.987 |
| Grade | ||||
| Well-differentiated | 1 | |||
| Moderately differentiated | 0.339 | 0.041 | 1.403 | 1.012–1.945 |
| Poorly differentiated | 0.696 | 0.000 | 2.007 | 1.382–2.914 |
| Undifferentiation | 1.271 | 0.017 | 3.565 | 1.254–10.134 |
| Surgical approach * | 0.129 | 0.124 | 1.137 | 0.965–1.341 |
| Examined of lymph node * | -0.176 | 0.000 | 0.838 | 0.762–0.921 |
| Extent of lymph node * | 0.172 | 0.135 | 1.187 | 0.947–1.488 |
| Depth of invasion * | 0.343 | 0.000 | 1.410 | 1.201–1.654 |
*not treated as factorial variable, due to the violation the PH assumption in some factorial levels of the variable.