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Number of Intestinal Biopsies from Patients with Crohn’s Disease to Reduce Standard Error to <25%
| Inflammatory Gene |
Ileum | Ascending Colon |
Transverse Colon |
Descending Colon |
Rectum |
|---|---|---|---|---|---|
| TNF-α | 3 | 2 | 2 | 1 | 2 |
| IL-1β | 2 | 3 | 3 | 2 | 2 |
| IP-10 | 4 | 4 | 4 | 3 | 2 |
| S100-A8 | 3 | 3 | 4 | 3 | 3 |
| IL-6 | 4 | 6 | 6 | 2 | 4 |
| IL-8 | 5 | 3 | 4 | 3 | 5 |
| MMP-3 | 8 | 4 | 6 | 6 | 5 |
The coefficient of variation was calculated for each gene for each segment. The number of biopsies required to reduce the standard error to less than 25% was determined.
