Table 2. PR/PR covariance pairs NOT in close proximity per the mature protease structure (3DJK).

Pos 1	Pos 2	Phi	Score	Pos 1	Pos 2
54	10	0.41
71	10	0.37	1.8	41	93
46	10	0.35	1.68	62	93
71	54	0.34
77	93	0.31	0.98	77	93
46	24	0.27
10	73	0.27	0.87	41	77
82	71	0.26
54	24	0.26
36	62	0.26	0.79	35	63
82	46	0.25
90	63	0.23	0.7	93	63
90	20	0.22	0.64	41	64
54	20	0.22	0.55	14	37
48	10	0.21

The left half lists the covariance pairs identified by Wu et al [42] and the right half lists those identified in this study. They are ranked by either Phi coefficient (left) or S score (right).