Table 3.
The prevalence of intra-amniotic inflammation and amniotic fluid matrix metalloproteinase-8 concentration, amniotic fluid white blood cell count according to the total grade of acute histologic chorioamnionitis
| Total grade of HCA | IAIc (n) | Pa | AF MMP-8 (ng/ml)d | Pb | AF WBC d | Pb |
|---|---|---|---|---|---|---|
| 0 (n=229) | 17.5% (40) | <0.001 | 1.8 (0.3–2845.5) | <0.001 | 2 (0–7200) | <0.001 |
| 1 (n=78) | 51.3% (40) | 25.9 (0.3–4202.7) | 5 (0–50000) | |||
| 2 (n=38) | 81.6% (31) | 229.7 (0.3–3929.0) | 405 (0–13248) | |||
| 3 (n=32) | 96.9% (31) | 486.2 (0.4–3392.0) | 478 (0–15000) | |||
| 4 (n=19) | 89.5% (17) | 422.4 (0.6–6142.6) | 892 (1–5800) | |||
| 5 (n=5) | 100.0% (5) | 257.0 (35.1–1007.3) | 198 (17–>1000) | |||
| 6 (n=11) | 81.8% (9) | 1475.7 (0.5–3116.7) | 1026 (1–8640) |
HCA, acute histologic chorioamnionitis; IAI, intra-amniotic inflammation; AF, amniotic fluid; MMP-8, matrix metalloproteinase-8; WBC, white blood cell
a
Linear-by-Linear Association
b
Kruskal-Wallis analysis test and Jonckheere-Terpstra test
c
AF MMP-8 concentration > 23 ng/mL
d
Values are given as median (range)