Table 3.

Mortality associated with specific infections in hospitalizations with myositis

	Prevalence of infection		Unadjusted OR for hospital mortality (95% CI)	Adjusted OR for hospital mortality (95% CI)#
	Survived (n=14707)	Died (n=700)
Infection (all)	3,873 (26%)	420 (60%)	4.2(3.6–4.9)
Selected bacterial	3,548 (24%)	406 (58%)	4.3(3.7–5.1)	3.5(3.0–4.1)
Meningitis / Encephalitis	46 (0.3%)	1 (0.1%)	0.5(0.1–3.3)
Cellulitis	959 (7%)	43 (6%)	0.9(0.7–1.3)
Endocarditis	35 (0.2%)	4 (0.6%)	2.4(0.9–6.8)
Pneumonia	1,860 (13%)	233 (33%)	3.4(2.9–4.1)
Pyelonephritis	107 (0.7%)	5 (0.7%)	1.0(0.4–2.4)
Septic arthritis / osteomyelitis	214 (1%)	9 (1%)	0.9(0.5–1.7)
Bacteremia	1,037 (7%)	285 (41%)	9.1(7.7–10.7)
Opportunistic fungal*	156 (1%)	24 (3%)	3.3(2.1–5.1)	2.5(1.5–4.0)
Mycobacterial**	76 (0.5%)	5 (0.7%)	1.4(0.6–3.4)	0.7(0.3–2)
Viral***	269 (2%)	16 (2%)	1.3(0.8–2.1)	1.0(0.6–1.7)

^#Regression model adjusts for age, gender, race/ethnicity, income, modified Charlson comorbidity index, the underlying diagnosis (DM vs. PM), non-elective admission, transfer from another hospital, length of stay, ILD, malignancy, CVD, and other pathogen-specific predictor variables in model; variables in shaded cells were not included.

^*Opportunistic fungal infections include aspergillus, disseminated candidiasis, coccidioidomycosis, histoplasmosis, and Cryptococcus.

^**Mycobacterial infections include tuberculosis and non-tuberculous mycobacterium.

^***Viral infections include HSV, VZV, and CMV.