Table 1.
Demographic and clinical characteristics
| Characteristics | OCD n=15 | Healthy control n=16 |
|---|---|---|
|
| ||
| Mean age in years (SD) | 30 (9) | 30 (8) |
|
| ||
| Number of males/females | 10/5 | 11/5 |
|
| ||
| Race-ethnicity | 6AA/5Cau/3His/1O | 6AA/6Cau/3His/1O |
|
| ||
| Mean age of OCD onset in years (SD) | 16 (10) | - |
|
| ||
| OCD in first degree relative (by subject self-report) | 4 | 0 |
|
| ||
| Mean Y-BOCS (SD) | 26 (3) | - |
|
| ||
| Mean HAM-D (SD) | 3 (4) | - |
|
| ||
| DSM-IV axis I psychiatric comorbidity: | ||
| None | 10 | 16 |
| Current specific or social phobia only | 2 | 0 |
| Current specific or social phobia with past | 2 | 0 |
| MDD | 0 | 0 |
| Past MDD only | 1 | 0 |
| History of substance or alcohol abuse/dependence | 0 | 0 |
|
| ||
| Current or past tic disorder | 0 | 0 |
|
| ||
| Treatment history: | ||
| Any prior exposure to psychotropic medications | 4 | 0 |
| SRIs | 3 | 0 |
| Mean wks (SD, range) since last SRI dose | 86 (61, 46–156) | 0 |
| Other medications (wks since last dose) | 1 (18) | 0 |
| Prior exposure therapy | 1 | 0 |
Abbreviations: AA, African-American; Cau, Caucasian; HAM-D, Hamilton Depression Rating Scale (17-item); HIS, Hispanic; MDD, major depressive disorder; O, other; OCD, obsessive-compulsive disorder; SD, standard deviation; SRI, serotonin reuptake inhibitor; wks, weeks; Y-BOCS, Yale-Brown Obsessive Compulsive Scale