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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Mol Aspects Med. 2015 Jan 8;42:105–118. doi: 10.1016/j.mam.2015.01.001

Figure 1. Structure of proinsulin.

Figure 1

Proinsulin is comprised sequentially of insulin B domain (blue), connecting C domain (which is disordered and therefore has no fixed structure), and insulin A domain (red). Six cysteines form three disulfide bonds that are labeled in yellow boxes. This figure was adapted from Liu, M., et al. 2010. PLoS ONE. 5(10):e13333.