Table 2.
Healthy control (raw) | Healthy control (normalizeda) | BDD (raw) | BDD (normalized*) | F | p | |
---|---|---|---|---|---|---|
GM and WM Volumes | ||||||
White matter | 383721 ± 52993 | 379279 ± 40636 | 0.08 | 0.78 | ||
Gray matter | 392550 ± 47144 | 383569 ± 38843 | 1.01 | 0.32 | ||
Thalamus (right) | 8517 ± 905 | 5541 ± 422 | 7916 ± 748 | 5496 ± 462 | 0.23 | 0.63 |
Thalamus (left) | 8261 ± 835 | 5707 ± 377 | 8102 ± 750 | 5610 ± 436 | 1.29 | 0.26 |
Anterior cingulate (right) | 4388 ± 922 | 2944 ± 555 | 4216 ±782 | 2895 ± 436 | 0.22 | 0.64 |
Anterior cingulate (left) | 4730 ± 1118 | 3145 ± 527 | 4612 ± 891 | 3186 ± 542 | 0.14 | 0.71 |
Medial orbital frontal cortex (right) | 5193 ± 748 | 3479 ± 395 | 5121 ± 639 | 3555 ± 404 | 0.83 | 0.36 |
Medial orbital frontal cortex (left) | 5404 ± 1009 | 3623 ± 620 | 51922 ± 125183 | 3539 ± 560 | 0.47 | 0.49 |
Left lnferior frontal gyrus | 11262 ± 2029 | 7526 ± 940 | 10570 ± 1639 | 7337 ± 1081 | 0.70 | 0.41 |
Caudate laterality | −0.0035 ± 0.0357 | −0.0017 ± 0.0513 | 0.04 | 0.85 | ||
GM thickness | ||||||
Anterior cingulate (left) | 5.65 ± 0.6 | 3.82 ± 0.57 | 5.66 ± 0.62 | 3.96 ± 0.61 | 1.57 | 0.21 |
Anterior cingulate (right) | 5.47 ± 0.46 | 3.71 ± 0.58 | 5.41 ± 0.47 | 3.77 ± 0.46 | 0.41 | 0.52 |
Medial orbitofrontal corte (left) | 2.46 ± 0.15 | 1.67 ± 0.22 | 2.43 ± 0.18 | 1.70 ± 0.22 | 0.52 | 0.47 |
Medial orbitofrontal cortex (right) | 2.44 ± 0.22 | 1.65 ± 0.25 | 2.46 ± 0.29 | 1.72 ± 0.27 | 1.83 | 0.18 |
Left inferior frontal gyrus | 7.91 ± 0.59 | 1.79 ± 0.23 | 7.87 ± 0.63 | 1.83 ± 0.25 | 0.97 | 0.33 |
Lingual gyrus (left) | 1.99 ± 0.11 | 1.35 ± 0.16 | 1.99 ± 0.13 | 1.39 ± 0.17 | 1.91 | 0.17 |
Precuneus (left) | 2.44 ± 0.17 | 1.65 ± 0.22 | 2.46 ± 0.19 | 1.72 ± 0.23 | 2.20 | 0.14 |
Precuneus (right) | 2.46 ± 0.17 | 1.67 ± 0.22 | 2.44 ± 0.21 | 1.70 ± 0.23 | 0.60 | 0.44 |
Lateral occipital cortex (left) | 2.21 ± 0.14 | 1.49 ± 0.18 | 2.24 ± 0.17 | 1.56 ± 0.21 | 3.10 | 0.08 |
Lateral occipital cortex (right) | 2.28 ± 0.17 | 1.54 ± 0.2 | 2.30 ± 0.19 | 1.61 ± 0.21 | 2.72 | 0.10 |
Values normalized to intracranial volumes: raw volume/total intracranial volume
106 Body dysmorphic disorder, BDD. Mean total volumes (mm3) and mean cortical thickness (mm) are listed for ROIs in healthy control and BDD participants, along with F and p-values from multivariate linear regressions of normalized volumes controlling for age, sex, and scanner.