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. Author manuscript; available in PMC: 2016 May 21.
Published in final edited form as: J Theor Biol. 2015 Mar 16;373:26–39. doi: 10.1016/j.jtbi.2015.03.004

Figure 5.

Figure 5

The macro-micro finite element (FE) model utilized in our investigations of MVIC deformations: (a) schematic diagram of tissue-level modeling of the region of interest of the MVAL tissue under equi-biaxial tension loading, and (b) schematic diagram of MVIC microenvironment modeling with tissue-level deformations as prescribed boundary displacements considering 37 uniformly distributed MV interstitial cells embedded in the layer-specific representative volume element (RVE). (tξ denotes layer-specific thickness)