Table 2.

Factors related to unresponsiveness to hepatitis B virus vaccination in the general population and patients with chronic kidney disease

General population	Patients with chronic kidney disease
Obesity	Dialysis
Smoking	Inflammation
	Administration route of vaccine
Diabetes mellitus
	Hyperparathyroidism
Lymphomas
	Co-existing HCV
Newborns and advanced age	Advanced age
Inflammation	Vitamin D deficiency
Celiac disease	Male gender
	Hypoalbuminemia
	Erythropoietin resistance
	IL-18 and IFN-y gene polymorphisms

HCV: Hepatitis C virus; IFN: Interferon; IL-18: Interleukin-18.