. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2014 Dec 1;67(4):390–396. doi: 10.1097/QAI.0000000000000333

TABLE 1.

PK Parameter Analysis of Pitavastatin and EFV

		Geometric Mean		Geometric Mean Ratio (90% CI)

PK Parameter	N	Pitavastatin With EFV	Pitavastatin Only	Pitavastatin With EFV/Pitvastatin Only
AUC_0-τ, ng·h·mL⁻¹	14	76	85.3	0.89 (0.73 to 1.09)
C_max, ng/mL	14	18.8	15.6	1.20 (0.79 to 1.83)
T_max, h^*	14	1.5 (1.0 to 2.3)	2.0 (0.9 to 3.0)

		EFV With Pitavastatin	EFV Only	EFV With Pitavastatin/EFV Only

AUC_0-τ, µg·h·mL⁻¹	14	44.4	49.5	0.90 (0.75 to 1.06)
C_max, µg·mL⁻¹	14	3.72	4.15	0.90 (0.66 to 1.22)
T_max, h^*	14	1.5 (1.0 to 2.3)	2.0 (0.9 to 3.0)

T_max reported as median (IQR).