. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2014 Dec 1;67(4):390–396. doi: 10.1097/QAI.0000000000000333

TABLE 2.

PK Parameter Analysis of Pitavastatin and DRV/r

		Geometric Mean		Geometric Mean Ratio (90% CI)

PK Parameter	N	Pitavastatin With DRV/r	Pitavastatin Only	Pitavastatin With DRV/r/Pitavastatin Only
AUC_0-τ, ng·h·mL⁻¹	10	56.9	62.8	0.91 (0.78 to 1.06)
C_max, ng/mL	10	23.2	24	0.93 (0.72 to 1.19)
T_max, h^*	10	0.5 (0.5 to 1.0)	0.5 (0.5 to 0.5)

		DRV/r With Pitavastatin	DRV/r Only	DRVr With Pitavastatin/DRV/r Only

AUC_0-τ, µg·h·mL⁻¹	14	76.7	70.9	1.08 (0.96 to 1.22)
C_max, µg/mL	14	6.78	6.61	1.03 (0.91 to 1.15)
T_max, h^*	14	0.5 (0.5 to 1.0)	0.5 (0.5 to 0.5)

T_max reported as median (IQR).