Table 2.

Quantitative myasthenia gravis (QMG) total score change (pharmacodynamic population)

	Placebo (n = 32)	Tirasemtiv 250 mg (n = 32)	Tirasemtiv 500 mg (n = 32)
Baseline QMG, mean total score (SD)	15.8 (5.3)	15.5 (5.1)	15.8 (5.0)
QMG change from baseline to hour 3, differences in LSM from placebo (95 % CI)	NA	0.1 (–1.0 to 1.3)	–0.2 (–1.3 to 0.9)
QMG change from baseline to hour 6, differences in LSM from placebo (95 % CI)	NA	–0.3 (–1.1 to 0.5)	–1.0 (–1.8 to –0.2)*

LSM = least square means; CI = confidence interval; NA = not applicable

*p < 0.05