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. 2015 Apr 14;5:24. doi: 10.1186/s13550-015-0096-0

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© Gaddy et al.; licensee Springer. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Rodent PET/CT imaging and kidney micro-dosimetry. (a) Maximum intensity projection (MIP) PET imaging time-course of a mouse treated with ⁶⁴Cu-MM-302. Data are not decay corrected. (b) Time-activity curves of the total kidney (squares) and renal pelvis (circles) generated from the mouse PET images. Data are not decay corrected. (c) Comparison of %ID/g in the total kidney and renal pelvis from mice treated with ⁶⁴Cu-MM-302 in independent imaging studies. Each data point represents an individual mouse (n = 15). Lines indicate the mean ± SD. The arrow denotes the mouse imaged during the ⁶⁴Cu-MM-302 dosimetry study. Data are decay corrected to the time of injection.