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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: J Immunol. 2011 Jul 8;187(4):1634–1642. doi: 10.4049/jimmunol.1100077

FIGURE 3.

FIGURE 3

Low dose of 4-1BB stimulation together with PD-L1 blockade increases cytokine production from LCMV-specific CD8 T cells. Experimental set-up as in Fig. 2A. A, Percentage of CD8 T cells from spleen-producing cytokines after 5 h stimulation with several LCMV peptides. B, Total numbers of IFN-γ cytokine-producing CD8 T cells after 5 h stimulation with several LCMV peptides. C, Total numbers of dual IFN-γ and TNF-α cytokine-producing CD8 T cells after 5 h stimulation with LCMV peptides. *p = 0.05, **p = 0.0016, ***p = 0.0010. Experiments were repeated four times.