Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 3;16(1):71. doi: 10.1186/s13059-015-0632-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Cwiklinski et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Analysis of the cysteine proteases belonging to F. hepatica cathepsin L (FhCL) and cathepsin B (FhCB) clades and their activators, the asparaginyl endopeptidases/legumains. (a) Representation of the number of genes identified for each FhCL clade and for the groups of FhCB and legumain genes, based on analysis by BLAST and manual annotation. The nucleotide identity is shown for each clade/group of genes (Clustal Omega). (b, c, d) Graphical representation of the expression for FhCL, FhCB and legumain proteases across the F. hepatica lifecycle in reads per kilobase per million (RPKM). In the case of the FhCL gene expression, all the genes within the same clade showed a similar pattern of expression, and so are represented here as an average log RPKM. Likewise in the case where multiple gene models were identified for a particular gene, which showed a similar level of expression, are represented here as an average log RPKM.