Table 3.
GO and KEGG enriched pathways for pairwise union of DE genes
| Category | KEGG term | Adjusted P value | GO category | Ontology | GO term | Adjusted P value |
|---|---|---|---|---|---|---|
| 4514 | Cell adhesion molecules (CAMs) | 0.0046 | GO:0032501 | BP | Multicellular organismal process | 6.64E-10 |
| 5144 | Malaria | 0.0059 | GO:0044707 | BP | Single-multicellular organism process | 4.57E-09 |
| 4142 | Lysosome | 0.0059 | GO:0006950 | BP | Response to stress | 5.06E-09 |
| 5143 | African trypanosomiasis | 0.0143 | GO:0044699 | BP | Single-organism process | 1.27E-08 |
| 4512 | ECM-receptor interaction | 0.0238 | GO:0044763 | BP | Single-organism cellular process | 9.29E-08 |
| 4145 | Phagosome | 0.0678 | GO:0050896 | BP | Response to stimulus | 1.01E-07 |
| 380 | Tryptophan metabolism | 0.0751 | GO:0004872 | MF | Receptor activity | 2.07E-06 |
| 5020 | Prion diseases | 0.0751 | GO:0002376 | BP | Immune system process | 2.07E-06 |
| 4610 | Complement and coagulation cascades | 0.0751 | GO:0007275 | BP | Multicellular organismal development | 2.07E-06 |
| 5416 | Viral myocarditis | 0.1024 | GO:0032502 | BP | Developmental process | 2.34E-06 |
| 4640 | Hematopoietic cell lineage | 0.1366 | GO:0007154 | BP | Cell communication | 5.70E-06 |
| 5414 | Dilated cardiomyopathy | 0.1513 | GO:0023052 | BP | Signaling | 6.39E-06 |
| 5150 | Staphylococcus aureus infection | 0.1513 | GO:0044700 | BP | Single organism signaling | 6.39E-06 |
| 590 | Arachidonic acid metabolism | 0.1513 | GO:0048731 | BP | System development | 7.32E-06 |
| 480 | Glutathione metabolism | 0.1683 | GO:0006955 | BP | Immune response | 7.32E-06 |
Enriched pathways for the pairwise union of all DE genes. Shown are the KEGG pathways and GO categories observed to be enriched when using the union of genes identified as DE (1,784 genes) in each pairwise comparison found in Table 2 ‘Permutation’. The table provides the category identifiers (in the case of GO the ontology: BP = biological process, CC = cellular component, MF = molecular function), the associated term or brief description, and the Benjamini-Hochberg adjusted P value.