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. 2015 Mar 8;6:13. doi: 10.1186/s13229-015-0003-6

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© Mosienko et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Isolation-induced ultrasonic vocalizations (USV) in Tph2 ^-/- mouse pups emitted at postnatal days (PND) 3, 6, and 9. (A) Total number (n), (B) average call duration in milliseconds (ms), (C) average call peak frequency in kilohertz (kHz), and (D) average call peak amplitude in decibel (dB) of isolation-induced USV emitted during the 10-min isolation from mother and littermates. Black circles: Tph2 wildtype (Tph2 ^+/+) control mice; grey circles: Tph2 heterozygous (Tph2 ^+/-) mice; white circles: Tph2 null mutant (Tph2 ^-/-) mice. Data are presented as means ± standard errors of the mean. *P < .050 Tph2 ^+/+ vs. Tph2 ^-/-.