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. 2015 Mar 8;6:13. doi: 10.1186/s13229-015-0003-6

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© Mosienko et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Developmental profile of Tph2 ^-/- mouse pups at postnatal days (PND) 3, 6, and 9. (A) Body temperature in degrees Celsius (°C) and (B) body weight in grams (g) in pups tested for isolation-induced ultrasonic vocalizations. Black circles: Tph2 wildtype (Tph2 ^+/+) control mice; grey circles: Tph2 heterozygous (Tph2 ^+/-) mice; white circles: Tph2 null mutant (Tph2 ^-/-) mice. Data are presented as means ± standard errors of the mean. **P < .005 Tph2 ^+/+ vs. Tph2 ^-/-; ***P < .001 Tph2 ^+/+ vs. Tph2 ^-/-; ^## P < .005 Tph2 ^+/- vs. Tph2 ^-/-; ^### P < .001 Tph2 ^+/- vs. Tph2 ^-/-. Please note that the error bars in B are too small to be visible.