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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: J Med Chem. 2008 Apr 17;51(10):2985–2991. doi: 10.1021/jm800031x

Table 1.

Partition Coefficients (Log P) and Rf Valuesa for 64Cu(ATSM/A) Imine Conjugates

compound log P TLC Rf (standard) radio-TLC Rf (64Cu complex)
1 2.30 ± 0.06 0.71 0.69
2 2.38 ± 0.08 0.77 0.75
3 2.28 ± 0.05 0.68 0.68
4 2.28 ± 0.02 0.69 0.70
5 2.38 ± 0.10 0.68 0.66
6 2.13 ± 0.04 0.54 0.57
64Cu-ATSMb 1.85 ± 0.05 0.56 0.61
a

Ethyl acetate/methanol (95:5) on silica TLC.

b

TLC performed on silica plates with EtAc as the eluent.