Table 2.

Biodistribution (%ID/g ± SD, n = 4) at 5, 20, 40, and 60 min of 1 and 3 in BALB/c Mice Bearing the EMT6 Mammary Tumor

tissue	5 min	20 min	40 min	60 min
Compound 1
blood	1.86 ± 1.97	3.62 ± 0.24	3.14 ± 0.19	2.91 ± 0.58
lung	19.87 ± 3.02	20.03 ± 3.23	18.49 ± 1.19	15.16 ± 4.21
liver	74.68 ± 4.46	61.29 ± 6.45	58.77 ± 5.69	52.91 ± 3.45
spleen	18.99 ± 6.98	13.97 ± 3.01	11.15 ± 0.63	8.82 ± 1.08
kidney	10.56 ± 6.41	13.28 ± 2.75	13.52 ± 1.00	12.44 ± 3.03
heart	4.25 ± 3.35	5.46 ± 0.63	4.84 ± 0.50	4.52 ± 0.25
brain	2.54 ± 1.40	2.80 ± 0.28	2.43 ± 0.17	2.58 ± 0.25
bone	1.37 ± 0.98	2.45 ± 0.40	2.44 ± 0.60	2.63 ± 0.70
tumor	2.69 ± 0.49	5.65 ± 1.76	5.56 ± 1.89	4.17 ± 0.37
intestines	7.21 ± 0.31	13.31 ± 2.92	18.56 ± 4.60	18.60 ± 8.93
Compound 3
blood	2.45 ± 0.99	3.10 ± 0.24	2.90 ± 0.82	2.20 ± 0.10
lung	26.92 ± 5.44	22.49 ± 4.96	17.73 ± 1.65	12.82 ± 0.48
liver	51.03 ± 8.61	65.94 ± 12.05	72.62 ± 5.28	44.99 ± 6.97
spleen	9.56 ± 1.66	9.21 ± 2.77	7.98 ± 2.11	4.60 ± 0.57
kidney	12.62 ± 2.59	17.88 ± 1.79	18.48 ± 2.21	11.69 ± 0.85
muscle	2.36 ± 0.50	3.21 ± 0.88	2.31 ± 0.87	1.30 ± 0.23
heart	5.85 ± 1.55	6.29 ± 0.89	5.58 ± 0.22	3.82 ± 0.24
brain	1.92 ± 0.29	2.54 ± 0.52	2.37 ± 0.11	1.46 ± 0.02
bone	2.32 ± 0.47	2.69 ± 0.58	2.97 ± 0.74	1.92 ± 0.23
tumor	1.78 ± 0.28	4.77 ± 2.07	4.42 ± 0.49	3.38 ± 0.15
intestines	5.71 ± 2.42	12.14 ± 1.99	20.41 ± 3.96	16.71 ± 0.37