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. 2015 Mar 31;16(1):63. doi: 10.1186/s13059-015-0624-2

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© Cheng et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Application of the HSM algorithm to the yeast phosphorylome. (A) The localization of kinases at different levels in the cytoplasm and nucleus. (B) The correlation of kinase properties with hierarchy. T, M, and B represent top, middle, and bottom levels, respectively.