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Severely atrophic Peyer’s patch in jejunum lacking lymphoid follicles and interfollicular areas, but with marked villous serositis. (A, goat 28). The organized lymphoid tissue is replaced by multiple small foci of epitheloid cells and MGCs and an extensive infiltrate of lymphocytes and plasma cells (A, B higher magnification of A, HE). There are no mycobacteria in the granulomatous infiltrate (C, immunohistochemistry MAP). Bar in A = 500 μm, bar in B = 100 μm, bar in C = 10 μm.
