Table 3.
Group | Animal No. | Liver | Hepatic LN | Spleen | Retropharyngeal LN | Tonsil | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Culture | gInf | MAP-IHC | Culture | gInf | MAP-IHC | Culture | gInf | MAP-IHC | Culture | gInf | MAP-IHC | Culture | gInf | MAP-IHC | ||
V1 | 7 | 0a) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
8 | 33.33 | +++b) | 0 | 25.00 | ++ | 0 | 12.50 | 0 | 0 | 10.42 | 0 | 0 | 26.04 | ++ | 0 | |
9 | 0 | 0 | 0 | 13.93 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
10 | 21.78 | ++ | 0 | 14.16 | 0 | 0 | 11.46 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
12 | 0 | + | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
V2 | 14c) | co. | 0 | 0 | 0 | ++ | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
16c) | 0 | 0 | 0 | 1.9 | + | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
17c) | 0 | 0 | 0 | 0 | ++ | 0 | 0 | 0 | 0 | 5.26 | 0 | 0 | 0 | 0 | 0 | |
18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
19 | 0 | +++ | 0 | 6.6 | ++ | 0 | 0 | 0 | 0 | 4.16 | + | 0 | 3.57 | 0 | 0 | |
20c) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
V3 | 27 | 12.50 | 0 | 0 | 8.33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
28 | co. | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
V4 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
35 | 16.78 | 0 | 0 | 8.33 | 0 | 0 | 0 | 0 | 0 | 8.33 | 0 | 0 | 0 | 0 | 0 | |
36d) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
37 | 4.29 | 0 | 0 | 22.50 | 0 | 0 | 0 | 0 | 0 | 7.94 | 0 | 0 | 0 | 0 | 0 | |
38 | co. | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
39 | co. | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
a)Growth Index b)granulomatous infiltrate: 0, none; +, mild, focal; ++, moderate, multifocal; +++, severe, diffuse; c)necropsy at 37–39 wpi; d)necropsy at 35 wpi; co. contaminated; na. not available; gInf, granulomatous infiltrate; MAP IHC, MAP antigen detected by IHC.