Figure 2.

A. Good match between histopathology and OCT with auxiliary lines created by the analysis software. The pink line represents edge detection. The top and bottom boundaries of the cartilage layer with extrapolation through the osteochondral defect are shown with the blue and green lines, respectively. The vertical red lines mark the location of healthy cartilage and the (start of the) osteochondral defect. Thickness is defined as the average distance between the blue and green line in healthy tissue regions. Area is computed from the area bounded by the pink line and green line in the defect region. Roughness is defined as the root-mean-square distance between the pink line and the blue line in the defect region. B. Fair match between OCT and histopathology, producing noticeable differences in the parameters repair tissue area and surface roughness. Definitions of the parameters are explained above and in the text.