Table 2. Efficacy Results in Intent to Treatment Population (ITT).
| Chemotherapy plus rmhTNF N = 265 No. (%) | Chemotherapy N = 264 No. (%) | Odds Ratio (95% CI) | p value | |
|---|---|---|---|---|
| Survival rate | ||||
| 1 year | 147 (55.5) | 111 (42) | 1.717 (1.217-2.422) | 0.002 |
| 2 years | 55 (20.8) | 53 (20.1) | 1.043 (0.683-1.591) | 0.846 |
| 3 years | 37 (14) | 28 (10.6) | 1.368 (0.81-2.309) | 0.24 |
| 4 years | 18 (6.8) | 1 (0.4) | 19.166 (2.54-144.645) | <0.001 |
| Response | ||||
| RR (CR+PR) | 102 (38.5) | 73 (27.7) | 1.637 (1.135-2.361) | 0.008 |
| CR | 4 (1.5) | 0 | / | 0.045 |
| PR | 98 (37) | 73 (27.7) | 1.535 (1.063-2.217) | 0.022 |
| SD | 105 (39.6) | 117 (44.3) | 0.825 (0.583-1.165) | 0.274 |
| PD | 58 (21.9) | 74 (28) | 0.719 (0.484-1.069) | 0.103 |
| Response duration (Month) | ||||
| First quartile | 3.6 | 2.8 | / | <0.001 |
| Median | 5.8 | 4.1 | / | <0.001 |
| Third quartile | 11 | 9.8 | / | <0.001 |
RR: Response Rate, CR: Complete Response, PR: Partial Response, SD: Stable Disease, PD: Progressive Disease, RR = CR+PR, CI: Confidence Intervals.