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. 2015 Apr 16;11:621–632. doi: 10.2147/TCRM.S67387

Figure 1.

Figure 1

Multiorgan and tissue pathophysiology of type 2 diabetes.

Notes: Adapted with permission from DeFronzo RA. Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58:773–795.4

Abbreviations: FFA, free fatty acids; GLP-1, glucagon-like peptide-1.