Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 22;4(3):e994374. doi: 10.4161/2162402X.2014.994374

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

© Catherine Flores, Christina Pham, David Snyder, Shicheng Yang, Luis Sanchez-Perez, Elias Sayour, Xiuyu Cui, Hanna Kemeny, Henry Friedman, Darell D Bigner, John Sampson, and Duane A Mitchell

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 1. — Highly invasive radiation and chemotherapy resistant glioma. (A) KR158B intracranial glioma is a highly invasive intracranial glioma that forms glioma islands and closely resembles primary human glioma. Shown is H&E stain of formalin-fixed, paraffin-embedded section (7 micron) taken from mice with established tumor. (B) Treatment with standard therapy with either whole brain radiation therapy (WBRT) or Temozolomide (TMZ) did not provide a survival benefit; however, the combination of WBRT+TMZ provided a modest increase in median survival, 38 d vs. 43 d, p = 0.0389 Gehan–Breslow–Wilcoxon test.