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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: Int J Cardiol. 2014 Oct 23;179:129–138. doi: 10.1016/j.ijcard.2014.10.140

Table 2.

Glutathione levels in placebo and Alda-1-treated post-MI cardiomyopathy rats

Parameter Sham Post-MI cardiomyopathy
Placebo Alda-1


GSH (nmol/mg) 3.06±0.44 4.29±0.21* 3.31±0.14
GSSG (nmol/mg) 0.36±0.03 0.61±0.05* 0.47±0.04
GSH/GSSG 8.34±0.82 7.14±0.48 7.56±1.15


Measurements of reduced glutathione (GSH), oxidized glutathione (GSSG) and reduced:oxidized glutathione ratio in cardiac sample from Sham (n=5), post-MI placebo (4 wks after MI, n=5) and post-MI Alda-1 treated (4 wks after MI, n=7) animals. Animals were treated for 4wks, starting 24hrs after permanent LAD occlusion surgery. Data were analyzed by one-way ANOVA followed by post-hoc Duncan. Error bars indicate SEM.

*

p<0.05 vs. control (sham);

p<0.05 vs. Post-MI Placebo rats.

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