Table 4.

Association between SNPs related to adult FeNO levels at P≤5×10⁻⁵ in the discovery sets and childhood FeNO levels (N=8,858) in pediatric studies of the EAGLE consortium

Chr	Locus	SNP	Baseline/Effect allele	Baseline allele frequency	Regression coefficient	Standard Error	P-value	Cochran P-value	I2
2	TAF1B	rs17364189	G/A	0.65	−0.0001	0.012	0.99	0.61	0
2	SLC8A1/HNRNPA1P57	rs2194437	G/C	0.92	−0.002	0.027	0.94	0.68	0
3	SLC6A11	rs2697159	G/A	0.46	−0.011	0.012	0.33	0.22	21.6
5	PLEKHG4B	rs7717734	T/C	0.30	−0.001	0.013	0.46	0.36	8.7
5	FSTL4	rs256257	T/C	0.42	−0.003	0.012	0.78	0.46	0
11	LOC100288844/LUZP2	rs12791623	T/A	0.90	−0.029	0.020	0.14	0.52	0
12	PLXNC1	rs3847800	A/G	0.16	0.008	0.016	0.61	0.51	0
15	RAB27A	rs2444043	C/T	0.50	−0.002	0.012	0.85	0.12	31.7
18	ZNF407/ZADH2	rs10163698	C/T	0.95	−0.048	0.034	0.16	0.10	35.9