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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: J Gastroenterol Hepatol. 2013 Aug;28(0 1):77–84. doi: 10.1111/jgh.12030

Figure 3.

Figure 3

Potential therapeutic targets for alcoholic liver disease identified in translational studies. The expression and/or activation of different mediators of alcoholic liver disease in liver tissue from patients have been investigated. These findings have been correlated with disease severity and the patient’s outcome. These targets include: CXC chemokines, IL-22/STAT3, TNF receptor superfamily, osteopontin, gut microbiota and LPS, endocannabinoids and inflammasomes. CB1, cannabinoid receptor 1; CB2, cannabinoid receptor 2; Gro-α growth-regulated α-protein; IL-8, interleukin 8; IL-22, interleukin 22; LPS, lipopolysaccharide; STAT3, signal transducer and activator of transcription 3; TNF, tumor necrosis factor; TLRs, toll-like receptors.