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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: J AIDS Clin Res. 2015 Jan 23;6(2):419. doi: 10.4172/2155-6113.1000419

Figure 3. HIV-positive donors show significantly diminished response to PPV23 compared to HIV-negative donors.

Figure 3

HIV-positive donor samples were compared to HIV-negative donor samples day 7 post-immunization with PPV23. Lymphocyte enriched peripheral blood samples stained with fluorescently labeled PPS14 or PPS23F were evaluated by flow cytometry for distribution of CD27 and IgM among PPS-selected CD19+ B cells. Post-immunization results for all HIV-positive individuals were categorized by CD4 counts and HAART usage. B cells were expressed as the number of PPS-selected CD19+ B cells per ml (A,B). In each sample, 100,000 events were recorded. Data are mean ± standard error of the mean. *p<0.05.