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. Author manuscript; available in PMC: 2015 Apr 21.
Published in final edited form as: ACS Chem Biol. 2015 Jan 27;10(4):1054–1063. doi: 10.1021/cb5007536

Figure 1.

Figure 1

(A) Structure of ZIMIR and the design of ZIMIR-HaloTag. ZIMIR-HaloTag contains a fluorescent zinc sensor and a reactive chloroalkane handle. (B) Structures of HaloTag AF488 and three fluorescein-based model compounds (Fluo HaloTag-1, -2, and -3) designed to optimize the linker length suitable for ZIMIR-HaloTag.