Table 3. Summary of the secondary associations with LDL subfractions in our analysis.
Gene | chr | SNP | log10 BFav(LDL subfractions) 1 | log10 BF(LDL-C) 1 | Imputation quality 2 | MAF 3 |
---|---|---|---|---|---|---|
APOE | 19 | rs157581 | 2.68 | 3.62 | 0.94 | 0.22 |
LPA | 6 | 6–161069320 | 2.65 | -0.44 | 0.61 | 0.36 |
CETP | 16 | rs11076175 | 2.34 | -0.05 | + | 0.18 |
See S1 Table in Supporting Information for other detailed results.
1 Results from a multivariate association analysis on the residuals obtained by regressing out the effects of the most strongly associated SNP in each gene.
2 Imputation quality reported from the software IMPUTE2 [10]; “+” for the typed SNP.
3 Minor allele frequency.