Figure 1.

N1 mutation does not affect splenic lymphocyte numbers following infection. Groups of five mice were infected intradermally with the indicated vaccinia viruses (VACVs) and splenic lymphocyte populations were counted at 7, 14, 21 and 28 days post-infection. (a, b) Total cell numbers. (c, d) T-cell and B-cell populations presented as total cell number (c) and as percentages of total lymphocytes (d). Results are expressed as mean ± SEM. Statistical comparison of cells from mock-infected mice with virus-infected mice: *P < 0·05, **P < 0·01.