Table 3. Calculated performance scores and ranking.

				Weight	Warfarin	Dabigatran 150 mg BID	Dabigatran 110 mg BID	Rivaroxaban 20 mg QD	Apixaban 5 mg BID
1. General (70 year old)
Overall risk-benefit assessment			Score	1	0.191	0.529		0.462	0.426
			Ranking		4	1		2	3
	Benefits		Score	0.631	0.284	0.57		0.506	0.393
			Ranking		4	1		2	3
		Prevention of ischemic stroke	Score	0.43	0.372	0.769		0.456	0.511
			Ranking		4	1		3	2
		Prevention of systemic embolism	Score	0.202	0.096	0.147		0.613	0.143
			Ranking		4	2		1	3
	Risks		Score	0.369	0.030	0.458		0.386	0.483
			Ranking		4	2		3	1
		Risk of intracranial bleeding	Score	0.252	0.000	0.639		0.230	0.598
			Ranking		4	1		3	2
		Risk of extracranial bleeding	Score	0.116	0.097	0.066		0.724	0.234
			Ranking		3	4		1	2
2. High risk of stroke (CHADS2 score ≥3)
Overall risk-benefit assessment			Score	1	0.116	0.462	0.392	0.271	0.686
			Ranking		5	2	3	4	1
	Benefits: Prevention of stroke or systemic embolism		Score	0.615	0.120	0.697	0.535	0.372	0.748
			Ranking		5	2	3	4	1
	Risks: Risk of major bleeding		Score	0.385	0.109	0.085	0.165	0.109	0.586
			Ranking		3	5	2	3	1
3. Primary stroke prevention
Overall risk-benefit assessment			Score	1		0.678	0.474	0.581	0.589
			Ranking			1	4	3	2
	Benefits		Score	0.791		0.753	0.468	0.642	0.629
			Ranking			1	4	2	3
		Prevention of stroke or systemic embolism	Score	0.132		0.758	0.383	0.575	0.503
			Ranking			1	4	2	3
		Prevention of death from vascular causes	Score	0.659		0.752	0.485	0.655	0.654
			Ranking			1	4	2	3
	Risks		Score	0.209		0.396	0.496	0.353	0.438
			Ranking			3	1	4	2
		Risk of intracranial bleeding	Score	0.143		0.393	0.525	0.194	0.377
			Ranking			2	1	4	3
		Risk of other local bleeding	Score	0.066		0.402	0.433	0.697	0.570
			Ranking			4	3	1	2
4. Secondary stroke prevention
Overall risk-benefit assessment			Score	1		0.585	0.901	0.581	0.601
			Ranking			3	1	4	2
	Benefits		Score	0.791		0.616	0.923	0.642	0.614
			Ranking			2	1	4	3
		Prevention of stroke or systemic embolism	Score	0.132		0.739	0.652	0.575	0.731
			Ranking			1	3	4	2
		Prevention of death from vascular causes	Score	0.659		0.592	0.978	0.655	0.590
			Ranking			3	1	2	4
	Risks		Score	0.209		0.467	0.817	0.353	0.554
			Ranking			3	1	4	2
		Risk of intracranial bleeding	Score	0.143		0.594	1.017	0.194	0.656
			Ranking			3	1	4	2
		Risk of other local bleeding	Score	0.066		0.194	0.383	0.697	0.332
			Ranking			4	2	1	3