Table 4.
Task Effect in cognitively normal subjects
Contrast | Brain region | Hemisphere | BA | Voxels | Coordinates (MNI, x,y,z) | T (Peak) | P (FWE) | ||
---|---|---|---|---|---|---|---|---|---|
PV >NV | Cuneus | R | 18 | 15,120 | 10 | −90 | 20 | 14.07 | <0.001 |
Precuneus | L | 31 | −8 | −62 | 26 | 13.07 | |||
Cingulate Gyrus | L | 31 | −6 | −40 | 38 | 11.50 | |||
Precuneus | L | 19 | 3,402 | −44 | −74 | 44 | 12.69 | <0.001 | |
Precuneus | L | 19 | −38 | −80 | 44 | 11.97 | |||
Middle Temporal Gyrus | R | 21 | 807 | −64 | −38 | −12 | 8.59 | <0.001 | |
Middle Temporal Gyrus | L | 21 | −56 | −20 | −16 | 6.69 | |||
Middle Frontal Gyrus | L | 6 | 1,300 | −42 | 8 | 46 | 8.29 | <0.001 | |
Medial Frontal Gyrus | L | 6 | −18 | 26 | 52 | 5.72 | |||
Superior Frontal Gyrus | L | 6 | −10 | 20 | 54 | 5.68 | |||
Inferior Frontal Gyrus | L | 13 | 2,461 | −46 | 32 | 4 | 7.72 | <0.001 | |
Medial Frontal Gyrus | L | 10 | −6 | 56 | 2 | 7.50 | |||
Superior Frontal Gyrus | L | 10 | −20 | 58 | 14 | 7.13 | |||
Anterior Cingulate Gyrus | R | na | 414 | 8 | 12 | −8 | 7.24 | <0.001 | |
Caudate | R | 12 | 14 | 6 | 6.48 | ||||
Caudate | L | na | 390 | −10 | 12 | −10 | 7.02 | <0.001 | |
Caudate | L | −12 | 10 | 8 | 6.91 | ||||
Parahippocampal Gryus | L | 30 | 182 | −22 | −40 | 0 | 6.34 | <0.001 | |
Parahippocampal Gyrus | L | 36 | −28 | −36 | −12 | 5.90 |
Indented regions subsumed under bolded regions of activation are part of the same cluster. One-hundred and seven cognitively normal individuals from the WRAP were included in a separate analysis to demonstrate the episodic memory task-effect
PV previously viewed faces, NV novel faces, BA Brodmann’s Area, MNI Montreal Neurological Institute, FWE Family Wise Error, L Left