Table 1. Clinical characteristics and laboratory parameters of children with and without atherogenic dyslipidemia.
| Variables | Children with atherogenic dyslipidemia (n = 62) | Children without atherogenic dyslipidemia (n = 221) |
|---|---|---|
| Age, (yrs) | 8.2 ± 3.9 | 8.3 ± 3.4 |
| Sex, Boys | 41 (66%) | 89 (40%) |
| Girls | 21 (34%) | 132 (60%) |
| BMI, (kg/m2) | 21.1 ± 5.3*** | 18.2 ± 3.5 |
| Systolic BP (mmHg) | 106.8 ± 10.7 | 108.1 ± 11.2 |
| Diastolic BP (mmHg) | 68.3 ± 10.0 | 70.3 ± 8.9 |
| Waist circumference (cm) | 73.0 ± 16.8*** | 61.5 ± 9.6 |
| Plasma lipids (mg/dl) | ||
| Total cholesterol | 187.3 ± 37.4 | 198.6 ± 38.7 |
| HDL-C | 32.9 ± 5.0*** | 58.8 ± 12.1 |
| Non-HDL-C | 154.4 ± 36.2*** | 139.8 ± 38.3 |
| Total triglycerides | 158.9 ± 83.2*** | 65.0 ± 19.2 |
| LDL-C | 122.5 ± 38.1 | 126.9 ± 37.4 |
| ApoB | 89.6 ± 27.5 | 82.4 ± 22.4 |
| LDL-C/Apo B | 1.39 ± 0.32** | 1.65 ± 0.75 |
| ApoAI | 126.0 ± 25.6*** | 155.3 ± 30.9 |
| Fasting Blood Glucose (mg/dl) | 77.2 ± 11.3*** | 69.1 ± 11.0 |
| Insulin (μU/ml) | 11.03 ± 8.36*** | 6.46 ± 4.23 |
| HOMA-IR | 2.14 ± 1.64*** | 1.09 ± 0.8 |
| hs-CRP (mg/dl) | 0.08 (0.04–0.22) * | 0.03 (0.00–0.12) |
| Adiponectin (μg/ml) | 3.75 (2.45–6.04) *** | 5.67 (3.88–7.41) |
| Metabolic Syndrome, n (%) | 26 (42) *** | 0 |
BMI, body mass index; BP, blood pressure; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; ApoB, apolipoprotein B; ApoAI, apolipoprotein AI; hs-CRP, high sensitivity C Reactive Protein; HOMA-IR, homeostasis model assessment of IR index.
hs-CRP and adiponectin values are reported as median (interquartile range)
* p<0.05;
** p<0.01;
*** p<0.001