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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Cell Immunol. 2015 Feb 25;295(1):36–45. doi: 10.1016/j.cellimm.2015.02.008

Fig. 4.

Fig. 4

Cytokine and degranulation profile of CEF peptide in vitro-expanded T-cells. (A) Representative intracellular cytokine density plots showing CEF-specific CD8+ TNFα+, IFNγ+ or CD107a+ T-cells for CIR and HD patients after in vitro restimulation using 9–10mer pooled CEF peptides. (B) Summary of frequency of multifunctional CD8+ T-cells (any 2 or 3 positive of TNFα+ and/or IFNγ+ and/or CD107a) among HD and CIR patients (C). CEF-specific IFNγ ELISPOT results of CEF-expanded T-cells from HD and CIR. p-Value by Wilcoxon Rank-Sum test.