Table 2.
Genes differentially expressed in response to addition of holo-Tf to the basolateral medium of confluent Caco-2 cell monolayers from day 14 to day 21 after cell seeding
| Affymetrix Probeset ID | Gene | Gene symbol | Fold changea | Uncorrected p valueb | FDRc |
|---|---|---|---|---|---|
| 226837_at | Sprouty-related, EVH1 domain containing 1 | SPRED1 | 2.19 | 9.77E−06 | 0.016 |
| 208891_at | Dual-specificity phosphatase 6 | DUSP6 | 1.51 | 1.01E−05 | 0.016 |
| 232321_at | Mucin 17 | MUC17 | 3.61 | 6.50E−06 | 0.016 |
| 227246_at | Pleiotropic regulator 1 | PLRG1 | −1.79 | 1.05E−05 | 0.016 |
| 209101_at | Connective tissue growth factor | CTGF | 1.64 | 6.89E−06 | 0.016 |
| 208383_s_at | Phosphoenolpyruvate carboxykinase 1 | PCK1 | 2.00 | 4.32E−06 | 0.016 |
| 211357_s_at | Aldolase B | ALDOB | 1.48 | 2.10E−05 | 0.027 |
aPositive values indicate increased expression following holo-Tf treatment (mean expression in holo-Tf-treated cells/mean expression in controls). Negative values indicate decreased expression following holo-Tf treatment (−mean expression in control cells/mean expression in holo-Tf treated cells)
bDerived from unpaired t tests with Bayesian correction (Limma) comparing data from microarrays for holo-Tf treated and control cells (n = 5 for both treatments)
cFalse discovery rate