Table 1. Characteristics of patients enrolled in the study.
| Characteristic | Severe sepsis/ | SIRS | Control |
|---|---|---|---|
| septic shock | |||
| (n = 94) | (n = 20) | (n = 20) | |
| Age, years | 63.7 ±12.2 | 63.2 ±11.8 | 58.8 ±9.2 |
| Gender, n (%) | |||
| female / male | 32 / 62 (66%) | 3 / 17 (85%) | 9 / 11 (55%) |
| Health scoring* | |||
| APACHE-II | 24.1 ±10.1 | ||
| SAPS-II | 50.2 ±17.9 | ||
| Site of infection, n (%) | |||
| Abdominal | 43 (46%) | ||
| Pneumonia | 27 (29%) | ||
| Soft tissue | 11 (12%) | ||
| Primary bacteremia | 7 (7%) | ||
| Endocarditis | 4 (4%) | ||
| Urogenital | 2 (2%) | ||
| Survival (28 days), n (%) | |||
| dead / survived | 22 / 72 (77%) | ||
| ΔSOFA (day 1–5) # , n (%) | |||
| ≤-4 | 18 (19%) | ||
| >-4, <4 | 47 (50%) | ||
| ≥4 | 15 (16%) | ||
| no data § | 14 (15%) |
* The patient health scores APACHE-II and SAPS-II were assigned at onset of sepsis (day 1).
# ΔSOFA was calculated as change in patients’ SOFA score between onset of sepsis (day 1) and sepsis day 5.
§ Patients died during the observation period.