Table 1. Baseline characteristics of included participants.
| Study A | Study B | |
|---|---|---|
| N enrolled | 336 | 60 |
| Age, N (%) | ||
| Less than 3 years old | 98 (29) | 14 (23) |
| 3 to 6 years old | 123 (37) | 13 (22) |
| 7 years or older | 115 (34) | 33 (55) |
| Mean age (SD) | 5.4 (4.1) | 7.3 (4.8) |
| Sex, N (%) | ||
| Male | 193 (57) | 32 (53) |
| Female | 143 (43) | 28 (47) |
| Ethnicity, N (%) | ||
| White | 260 (77) | 38 (63) |
| Asian | 33 (10) | 14 (23) |
| Black | 10 (3) | 4 (7) |
| Mixed | 19 (6) | 4 (7) |
| Other | 12 (4) | 0 |
| Not stated/unknown | 2 (1) | 0 |
| Eczema severity (POEM) 1 | ||
| Mean (SD) | 17 (6) | 13 (7) |
| Eczema severity (SASSAD), N (%) 1 | ||
| 10–19 | 143 (43) | N/A |
| >20 | 192 (57) | N/A |
| Mean (SD) | 25.6 (13.6) | N/A |
| Three Item Severity (TIS) | ||
| Mean (SD) | 3.9 (1.8) | 3.1 (1.5) |
| Filaggrin status, N (%) | ||
| Presence of a mutation | 94 (28) | 10 (17) |
| Absence of a mutation | 218 (65) | 44 (73) |
| Unknown | 24 (7) | 6 (10) |
1 There was 1 missing value for SASSAD in Study A, and I missing value for POEM in both Study A and Study B.
Abbreviations: Standard Deviation (SD), Patient Oriented Eczema Measure (POEM), Six Area, Six Sign Atopic Dermatitis (SASSAD), Not applicable (N/A)