Table 3. Odds of experiencing an AE flare (escalation of treatment) and odds of using anti-inflammatory medication by self-reported bother scores each day.
| Escalation of treatment | Use of anti-inflammatory medication* | ||
|---|---|---|---|
| Bother score | Study A (n = 334) Odds ratio (95% CI) | Study B (n = 59) Odds ratio (95% CI) | Study A (n = 334) Odds ratio (95% CI) |
| 0 | 0.01 (0.004, 0.01) | 0.08 (0.06, 0.11) | 0.05 (0.04, 0.07) |
| 1 | 0.04 (0.03, 0.05) | 0.15 (0.11, 0.21) | 0.07 (0.05, 0.08) |
| 2 | 0.19 (0.16, 0.23) | 0.27 (0.21, 0.35) | 0.25 (0.22, 0.29) |
| 3 | 0.42 (0.37, 0.49) | 0.63 (0.50, 0.80) | 0.51 (0.46, 0.57) |
| 4 | 1.00 | 1.00 | 1.00 |
| 5 | 2.16 (1.90, 2.45) | 1.43 (1.11, 1.84) | 1.84 (1.66, 2.05) |
| 6 | 4.06 (3.55, 4.65) | 2.73 (2.05, 3.65) | 3.23 (2.87, 3.63) |
| 7 | 7.78 (6.70, 9.03) | 4.21 (3.08, 5.76) | 5.46 (4.77, 6.24) |
| 8 | 13.24 (11.21, 15.64) | 6.43 (4.43, 9.35) | 6.10 (5.22, 7.12) |
| 9 | 19.36 (15.67, 23.92) | 6.91 (4.41, 10.81) | 6.23 (5.08, 7.64) |
| 10 | 34.18 (25.54, 45.73) | 7.34 (4.69, 11.49) | 8.47 (6.37, 11.27) |
*Topical corticosteroid / topical calcineurin inhibitors