Table 5. Mean increase in AE severity scales per unit increase in number of days when treatment escalated and use of a topical anti-inflammatory.
Study A *Escalation of treatment (95% CI) | Correlation coefficient | Study B * Escalation of treatment (95% CI) | Correlation coefficient | Study A *Anti-inflammatory medication (95% CI) | Correlation coefficient | |
---|---|---|---|---|---|---|
n | 331 | 59 | 331 | |||
POEM | 0.51 (0.33, 0.69); p<0.001 | 0.527 | 0.63 (0.10, 1.16); p = 0.021 | 0.609 | 0.55 (0.40, 0.71; p<0.001) | 0.528 |
TIS | 0.04 (-0.01,0.09); p = 0.138 | 0.551 | 0.08 (-0.07, 0.22); p = 0.321 | 0.61 | 0.06 (0.02, 0.11; p = 0.003) | 0.545 |
SASSAD | 0.43 (0.14, 0.71); p = 0.004 | 0.762 | N/A | N/A | 0.53 (0.28, 0.78; p<0.0001) | 0.757 |
*Increase in outcome measure for one unit increase in number of days in the previous week that treatment was escalated of topical anti-inflammatory medication was used. Uses data from weeks 4, 12 and 16