. 2015 Apr 21;10(4):e0123454. doi: 10.1371/journal.pone.0123454

Table 2. Normal rats.

Tail amputation	Bleeding time	Amount of bleeding	PLT before	PLT after	HCT before	HCT after	PT	APTT	TT	FIB
Tail amputation	min	mL	x10⁹/L	x10⁹/L	L/L	L/L	ratio (PR)	ratio	sec	g/L
Control	18±3	1.92±1.1	853±173	605±35	0.446±0.03	0.430±0.04	1.30±0.22	0.45± 0.16	34± 12	1.6± 0.22
BPC ug	7±2^*	0.21±0.06^*	820±167	685± 22^*	0.461±0.03	0.453±0.03	1.32±0.25	0.41± 0.17	40± 11	1.8± 0.17
BPC ng	8±2^*	0.24±0.04^*	831±178	675± 17^*	0.454±0.04	0.446±0.03	1.35±0.21	0.42± 0.11	41± 13	1.7± 0.19
L-arginine	29±4^*	1.63±1.2	781±123	702± 30^*	0.497±0.03	0.476±0.03	1.29±0.21	0.64± 0.18	35± 9	1.8± 0.23
L-NAME	7±2^*	0.75±0.15^*	677± 105^*	601±40	0.481±0.04	0.454±0.03	1.28±0.19	0.66± 0.21	30± 8	1.8± 0.18
L-NAME+ L-arginine	21±3	0.8±0.24^*	695±94^*	442± 15^*	0.482±0.05	0.468±0.03	1.24±0.22	0.51± 0.13	46± 14	1.8± 0.21
L-arginine+BPC 157 ug	9±2^*	0.57±0.11^*	801±189	694± 39^*	0.506±0.04	0.490±0.04	1.28±0.21	0.49± 0.17	39± 11	1.8± 0.27
L-NAME+ BPC 157 ug	8±2^*	0.40±0.12^*	758±122	654± 25^*	0.472±0.03	0.465±0.04	1.30±0.22	0.49± 0.18	40± 10	1.8± 0.19
L-NAME+L-arginine+ BPC 157 ug	10±3^*	0.30±0.09^*	788±133	655± 31^*	0.479±0.03	0.466±0.03	1.34±0.23	0.5± 0.13	48± 13	1.8± 0.18

Tail amputation, bleeding time, amount of bleeding, PLT, HCT, PT, APTT, TT, FIB, values in normal rats (10 rats at least per group) with amputation challenged with BPC 157 (10 μg/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg) given alone and/or together,applied intraperitoneally, at 30 minutes before amputation while controls received simultaneously an equivolume of saline (5ml/kg intraperitoneally). Mean ± SD,

*P<0.05 at least vs. control.